Exploring the Potential of CRISPR-Cas9 in Targeting the Genetics of Aging to Extend Human Lifespan

Melina Salgado

ABSTRACT 

This project investigates the potential of editing genes and cells that have grown old and are growing, in order to delay cellular aging and extend the human lifespan. In this paper, the initial section would go over the causes of cellular aging. Whether this is a natural cause or a disease, utilizing CRISPR could differentially impact aged cells. A comprehensive look through of CRISPR’s development moving into the gene editing topic, from its discovery to current applications. Central idea of the project is the identification of specific genes and cellular processes that drive the aging process, simplifying targeted alterations aimed to control or reverse age-associated changes. A review of peer-reviewed papers will elaborate on methodologies used by scientists and engineers. Additionally, the project will delve into the biological processes that control aging, evaluating how genetic modifications will alter these processes, while considering safety precautions, such as unwanted consequences. Finally, the implications of CRISPR technology and its positive outcome on extending individual health will be discussed, highlighting both immediate impact and long-term effects on human well-being and longevity throughout the years. 

Keywords: CRISPR-Cas9, aging, genetics of aging, age-related diseases, and gene editing

Polygence Melina Draft.pdf

Download PDF • 489KB